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2017

Cecilia Ansalone, Lotta Utriainen, Simon Milling, Carl S Goodyear. Gut Inflammation in HLA‐B27 Transgenic Rats Alters The Monocyte Compartment And Its Osteoclastogenic Potential. Arthritis & Rheumatology. 2017. DOI: 10.1002/art.40154

John van Tuyn, Farah Jaber-Hijazi, Douglas MacKenzie, John J Cole, Elizabeth Mann, Jeff S Pawlikowski, Taranjit Singh Rai, David M Nelson, Tony McBryan, Andre Ivanov, Karen Blyth, Hong Wu, Simon Milling, Peter D Adams. Oncogene-Expressing Senescent Melanocytes Upregulate MHC Class II, A Candidate Melanoma Suppressor Function. Journal of Investigative Dermatology . 2017. In press, accepted manuscript.

A Schridde, CC Bain, JU Mayer, J Montgomery, E Pollet, B Denecke, SWF Milling, SJ Jenkins, M Dalod, S Henri, B Malissen, O Pabst. Tissue-specific differentiation of colonic macrophages requires TGFβ receptor-mediated signaling. Mucosal Immunology. 2017. doi: 10.1038/mi.2016.142

Francesco Ciccia, Giuliana Guggino, Aroldo Rizzo, Riccardo Alessandro, Michele Maria Luchetti, Simon Milling, Laura Saieva, Heleen Cypers, Tommaso Stampone, Paola Di Benedetto, Armando Gabrielli, Alessio Fasano, Dirk Elewaut, Giovanni Triolo. Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis. Annals of the rheumatic diseases. 2017. 76:1123–1132. doi:10.1136/annrheumdis-2016-210000

Mariola Kurowska-Stolarska, Stefano Alivernini, Emma Garcia Melchor, Aziza Elmesmari, Barbara Tolusso, Clare Tange, Luca Petricca, Derek S Gilchrist, Gabriele Di Sante, Chantal Keijzer, Lynn Stewart, Clara Di Mario, Vicky Morrison, James M Brewer, Duncan Porter, Simon Milling, Ronald D Baxter, David McCarey, Elisa Gremese, Greg Lemke, Gianfranco Ferraccioli, Charles McSharry, Iain B McInnes. MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis. Nature Communications. 2017. 8:15877. DOI: 10.1038/ncomms15877

Johannes U Mayer, Mimoza Demiri, William W Agace, Andrew S MacDonald, Marcus Svensson-Frej, Simon W Milling. Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon. Nature Communications. 2017. 8:15820. DOI: 10.1038/ncomms15820

Heather E Hulme, Lynsey M Meikle, Hannah Wessel, Nicole Strittmatter, John Swales, Carolyn Thomson, Anna Nilsson, Robert JB Nibbs, Simon Milling, Per E Andren, C Logan Mackay, Alex Dexter, Josephine Bunch, Richard JA Goodwin, Richard Burchmore, Daniel M Wall. Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection. Scientific Reports. 2017. 7: 2786. DOI:10.1038/s41598-017-03100-5

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2016

Alberto Bravo-Blas, Hannah Wessel, Simon Milling. Microbiota and arthritis: correlations or cause? Current opinion in rheumatology. 2016. 28 (2); 161-167.

SA Houston, V Cerovic, C Thomson, J Brewer, AM Mowat, S Milling. The lymph nodes draining the small intestine and colon are anatomically separate and immunologically distinct. Mucosal Immunology. 2016. 9 (2); 468-478.

Charlotte L Scott, Pamela B Wright, Simon WF Milling, Allan McI Mowat. Isolation and identification of conventional dendritic cell subsets from the intestine of mice and men. Dendritic Cell Protocols. 2016. Methods in Molecular Biology; 101-118.

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2015

Emma C Mackley, Stephanie Houston, Clare L Marriott, Emily E Halford, Beth Lucas, Vuk Cerovic, Kara J Filbey, Rick M Maizels, Matthew R Hepworth, Gregory F Sonnenberg, Simon Milling, David R Withers. CCR7-dependent trafficking of RORγ+ ILCs creates a unique microenvironment within mucosal draining lymph nodes. Nature Communications. 6:5862. DOI: 10.1038/ncomms6862

V Cerovic, SA Houston, J Westlund, L Utriainen, ES Davison, CL Scott, CC Bain, Thorsten Joeris, WW Agace, RA Kroczek, AM Mowat, U Yrlid, S WF Milling. Lymph-borne CD8α+ dendritic cells are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells. Mucosal Immunology. 2015. 8 (1), 38

PB Wright, A McEntegart, D McCarey, IB McInnes, S Siebert, SWF Milling. Ankylosing spondylitis patients display altered dendritic cell and T cell populations that implicate pathogenic roles for the IL-23 cytokine axis and intestinal inflammation. Rheumatology. 2015. 55 (1), 120-132

Osiris Marroquin Belaunzaran, Sascha Kleber, Stefan Schauer, Martin Hausmann, Flora Nicholls, Maries Van den Broek, Sravan Payeli, Adrian Ciurea, Simon Milling, Frank Stenner, Jackie Shaw, Simon Kollnberger, Paul Bowness, Ulf Petrausch, Christoph Renner. HLA-B27-homodimer-specific antibody modulates the expansion of pro-inflammatory T-cells in HLA-B27 transgenic rats. PloS one. 2015. 10 (6), e0130811

Charlotte L Scott, Calum C Bain, Pamela B Wright, Dorine Sichien, Knut Kotarsky, Emma K Persson, Katarzyna Luda, Martin Guilliams, Bart N Lambrecht, William W Agace, S WF Milling, AM Mowat. CCR2+ CD103− intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells. Mucosal Immunology. 2015. 8 (2), 327

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2014

Laura B Ford, Vuk Cerovic, Simon WF Milling, Gerard J Graham, Chris AH Hansell, Robert JB Nibbs. Characterization of conventional and atypical receptors for the chemokine CCL2 on mouse leukocytes. The Journal of Immunology. 2014. 193 (1), 400-411

V Cerovic, CC Bain, AM Mowat, SWF Milling. Intestinal macrophages and dendritic cells: what's the difference? Trends in Immunology. 2014. 35 (6), 270-277

Kirsty McHugh, Oliwia Rysnik, Simon Kollnberger, Jacqueline Shaw, Lotta Utriainen, Mohammad Hussein Al-Mossawi, Sravan Payeli, Osiris Marroquin, Simon Milling, Christoph Renner, Paul Bowness. Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply. Annals of the rheumatic diseases. 2014. 73 (4), 763-770

JCJ Martin, G Bériou, M Heslan, C Chauvin, L Utriainen, A Aumeunier, CL Scott, A Mowat, V Cerovic, SA Houston, M Leboeuf, FX Hubert, C Hémont, M Merad, S Milling, R Josien. Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunology. 2014. 7 (1), 101

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2013

Cerovic V, Houston SA, Scott CL, Aumeunier A, Yrlid U, Mowat AM, Milling S. Intestinal CD103- dendritic cells migrate in lymph and prime effector T cells. Mucosal Immunology. 2013 Jan; 6 (1): 104-13.

Wright P, Utriainen L, Milling S. Dendritic cells and regulatory T cells in spondyloarthritis. Current Opinion in Rheumatology. 2013. Jul;25(4):440-7

Dunne KA, Allam A, McIntosh A, Houston SA, Cerovic V, Goodyear CS, Roe AJ, Beatson SA, Milling SW, Walker D, Wall DM. Increased S-Nitrosylation and Proteasomal Degradation of Caspase-3 during Infection Contribute to the Persistence of Adherent Invasive Escherichia coli (AIEC) in Immune Cells. PLoS One. 2013 Jul 4;8(7)

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2012

Utriainen L, Firmin D, Wright P, Cerovic V, Breban M, McInnes I, Milling S. Expression of HLA-B27 Causes Loss of Migratory Dendritic Cells in a Rat Model of Spondyloarthritis. Arthritis & Rheumatism. 2012. Oct ; 64 (10): 3199-209.

Shekhar S, Milling S, Jenkins C, Macpherson GG. Identification and phenotypic characterization of γδ T cells in rat lymph. Res Vet Sci. 2012. Aug;93(1):168-71.

Shekhar S, Milling S, Yang X. Migration of γδ T cells in steady-state conditions. Vet Immunol Immunopathol. 2012 Jun 15;147(1-2):1-5

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2011

Lee KM, McKimmie CS, Gilchrist DS, Pallas KJ, Nibbs RJ, Garside P, McDonald V, Jenkins C, Ransohoff R, Liu L, Milling S, Cerovic V and Graham GJ. D6 facilitates cellular migration, and fluid flow, to lymph nodes by suppressing lymphatic congestion. Blood. 2011. Dec 1;118(23):6220-9.

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Milling S, Yrlid U, Cerovic V, MacPherson GG. Subsets of migrating intestinal dendritic cells. Immunological Reviews. 2010; (234): 259-67.

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2010

2009

Milling, S and MacPherson, G. Isolation of Rat Intestinal Lymph DC. In: Dendritic Cell Protocols. Methods In Molecular Biology. 2009; 595.

Milling S, Jenkins C, Yrlid U, Cerovic V, Edmond H, McDonald V, Nassar M, MacPherson GG. Steady state migrating intestinal dendritic cells induce potent inflammatory responses in naïve CD4 T cells. Mucosal Immunology. 2009 Mar;2(2):156-65.

Cerovic V, McDonald V, Nassar M,  Paulin S, MacPherson GG, and Milling S. New insights into the roles of dendritic cells in intestinal immunity and tolerance. Int Rev Cell Mol Biol. 2009 (272): 33-105

Cerovic V,  Jenkins C, Barnes AGC, Milling S, MacPherson GG, and Klavinskis LS. Hyporesponsiveness of intestinal dendritic cells to TLR stimulation is limited to TLR4. Journal of Immunology. 2009 Feb 15;182(4):2405-15.

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Silver KL, Crockford TL, Bouriez-Jones T, Milling, S, Lambe T, and Cornall RJ. 2007. MyD88-dependent autoimmune disease in Lyn-deficient mice. European Journal of Immunology. 2007 Oct; 37(10):2734-43

Milling S, Yrlid U, Jenkins C, Richards C, Williams N and MacPherson GG. Regulation of intestinal immunity: effects of the oral adjuvant E. coli heat labile enterotoxin on migrating dendritic cells. European Journal of Immunology. 2007; (37):87-99.

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2007

2006

Milling S, Jenkins C and MacPherson GG. Collection of lymph-borne dendritic cells in the rat. Nature Protocols. 2006; (1): 2263-70.

Yrlid U, Cerovic V, Milling S, Jenkins  C, Zhang J, Crocker P, Klavinskis L, MacPherson GG. Plasmacytoid Dendritic Cells Do Not Migrate in Intestinal or Hepatic Lymph . Journal of Immunology 2006; (177):6115-6121

Yrlid U, Cerovic V, Milling S, Jenkins C,  Klavinskis LS, MacPherson GG. A distinct subset of intestinal dendritic cells responds selectively to oral TLR7/8 stimulation.  European Journal of Immunology. 2006 Oct;36(10):2639-48.

Yrlid U, Milling S, Miller J, Cartland S, Jenkins C, and G. Gordon MacPherson. Regulation of intestinal dendritic cell migration and activation by plasmacytoid dendritic cells, TNF and type 1 IFNs after feeding a TLR7/8 ligand. Journal of Immunology. 2006, 176: 5205-5212

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2005

Milling S, Cousins L, and MacPherson GG. How do dendritic cells sample the intestinal environment? Trends In Immunology, 2005 Jul;26(7):349-52

MacPherson GG, Milling S, Turnbull E  and Yrlid U. (2005). Steady state migration of dendritic cells in lymph. Dendritic cells. Edited by M Lutz and A. Steinkasserer, WILEY - VCH publishers Hoboken New Jersey, USA, 279-294

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MacPherson G, Milling S, Yrlid U, Cousins L, Turnbull E, Huang FP. Uptake of antigens from the intestine by dendritic cells. Ann N Y Acad Sci. 2004 Dec;1029:75-82.

Milling S, and MacPherson,GG. Dendritic Cells Control the Balance between Tolerance and Autoimmunity. In: Stem Cell Therapy for Autoimmune Disease. Eds Burt, R.K. and Marmont, A.M. Landes Bioscience 2004

Milling S, Silvers,W.K, Sai,T., and Mintz B. Inhibition of melanoma growth after treatment with dendritic cells In the Tyr-SV40E murine model requires CD4+ T cells. Melanoma Research 2004 Dec;14(6):555-62

MacPherson G, Milling S, Yrlid U, Cousins L, Turnbull E, Huang FP. Uptake of antigens from the intestine by dendritic cells. Ann N Y Acad Sci. 2004 Dec;1029:75-82.

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2004

2002

Milling S, Silvers WK. Sai T., and Mintz B. Decline in MHC class I expression with increasing thickness of cutaneous melanomas in standard‑strain transgenic mouse models. Melanoma Research. 2002 Jun;12(3):221-30.

Sai T, Milling S. and Mintz B. Freezing and thawing of bone marrow-derived murine dendritic cells with subsequent retention of immunophenotype and of antigen processing and presentation characteristics. Journal of Immunological Methods. 2002 Jun 1;264(1-2):153-62.

Prowse AH, Vanderveer L, Milling S, Pan Z, Dunbrack RL, Xu X, and Godwin AK. OVCA2 is down-regulated and degraded during retinoid-induced apoptosis. International Journal of Cancer. 2002 May 10;99(2):185-92.

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